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PAB35552 AMPD1 Polyclonal Antibody

价格:    320.00元

  • Catalog:    PAB35552
  • Application:    WB,IHC,ELISA
  • Reactivity:    Human,Mouse,Rat

库存 800 件

PAB35552 AMPD1 Polyclonal Antibody

320.00元

Catalog : PAB35552
Application : WB,IHC,ELISA
Reactivity : Human,Mouse,Rat
Product Information


Product name

AMPD1 Polyclonal Antibody

Isotype

IgG

Form

Lyophilized or Liquid

Tested applications

WB,IHC,ELISA

Species reactivity

Human,Mouse,Rat

Host Species

Rabbit

Purity

Affinity purification


Immunogen Information


Immunogen

A synthetic peptide of human AMPD1

Calculated molecular weight

89kDa/90kDa

Observed molecular weight 

80kDa

Swiss Prot

P23109

Gene ID (NCBI)

270

Alternative Names

MAD;MADA;MMDD


Application Notes


The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

WB

1:500 - 1:2000

IHC

1:50 - 1:100

 

1            2                       

Western blot analysis of extracts of various cell lines, using AMPD1 antibody.


Immunohistochemistry of paraffin-embedded human esophagus using AMPD1 antibody.


       3                  

Immunohistochemistry of paraffin-embedded rat brain using AMPD1 antibody.



     

Background


Adenosine monophosphate deaminase 1 catalyzes the deamination of AMP to IMP in skeletal muscle and plays an important role in the purine nucleotide cycle. Two other genes have been identified, AMPD2 and AMPD3, for the liver- and erythocyte-specific isoforms, respectively. Deficiency of the muscle-specific enzyme is apparently a common cause of exercise-induced myopathy and probably the most common cause of metabolic myopathy in the human. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene.   

                                                                                                 

Storage


Storage instructions

Store at -20. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.