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PAB36102 COL6A1 Polyclonal Antibody

价格:    320.00元

  • Catalog:    PAB36102
  • Application:    WB,IHC,ELISA
  • Reactivity:    Human,Mouse

库存 800 件

PAB36102 COL6A1 Polyclonal Antibody

320.00元

Catalog : PAB36102
Application : WB,IHC,ELISA
Reactivity : Human,Mouse
Product Information

 

Product name

COL6A1 Polyclonal Antibody

Isotype

IgG

Form

Lyophilized or Liquid

Tested applications

WB,IHC,ELISA

Species reactivity

Human,Mouse

Host Species

Rabbit

Purity

Affinity purification

 

Immunogen Information


Immunogen

Recombinant protein of human COL6A1

Calculated molecular weight

108kDa

Observed molecular weight 

109kDa

Swiss Prot

P12109

Gene ID (NCBI)

1291

Alternative Names

BTHLM1;OPLL;UCHMD1


Application Notes



The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

WB

1:500 - 1:2000

IHC

1:50 - 1:200

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Western blot analysis of extracts of various cell lines, using COL6A1 antibody.


Immunohistochemistry of paraffin-embedded human lung using COL6A1 antibody.


Background


The collagens are a superfamily of proteins that play a role in maintaining the integrity of various tissues. Collagens are extracellular matrix proteins and have a triple-helical domain as their common structural element. Collagen VI is a major structural component of microfibrils. The basic structural unit of collagen VI is a heterotrimer of the alpha1(VI), alpha2(VI), and alpha3(VI) chains. The alpha2(VI) and alpha3(VI) chains are encoded by the COL6A2 and COL6A3 genes, respectively. The protein encoded by this gene is the alpha 1 subunit of type VI collagen (alpha1(VI) chain). Mutations in the genes that code for the collagen VI subunits result in the autosomal dominant disorder, Bethlem myopathy.   


Storage


Storage instructions

Store at -20. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.