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PAB35914 UVRAG Polyclonal Antibody

价格:    320.00元

  • Catalog:    PAB35914
  • Application:    WB,IHC,ELISA
  • Reactivity:    Human,Mouse,Rat

库存 800 件

PAB35914 UVRAG Polyclonal Antibody

320.00元

Catalog : PAB35914
Application : WB,IHC,ELISA
Reactivity : Human,Mouse,Rat
Product Information


Product name

UVRAG Polyclonal Antibody

Isotype

IgG

Form

Lyophilized or Liquid

Tested applications

WB,IHC,ELISA

Species reactivity

Human,Mouse,Rat

Host Species

Rabbit

Purity

Affinity purification


Immunogen Information


Immunogen

Recombinant protein of human UVRAG

Calculated molecular weight

35kDa/78kDa

Observed molecular weight 

100kDa

Swiss Prot

Q9P2Y5

Gene ID (NCBI)

7405

Alternative Names

DHTX;p63;VPS38


Application Notes


   

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

WB

1:500 - 1:2000

IHC

1:50 - 1:100

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Western blot analysis of extracts of various cell lines, using UVRAG antibody.


Immunohistochemistry of paraffin-embedded human liver injury using UVRAG antibody.

 

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Immunohistochemistry of paraffin-embedded rat lung using UVRAG antibody.


Immunohistochemistry of paraffin-embedded mouse lung using UVRAG antibody.


Background

   

This gene complements the ultraviolet sensitivity of xeroderma pigmentosum group C cells and encodes a protein with a C2 domain. The protein activates the Beclin1-PI(3)KC3 complex, promoting autophagy and suppressing the proliferation and tumorigenicity of human colon cancer cells. Chromosomal aberrations involving this gene are associated with left-right axis malformation and mutations in this gene have been associated with colon cancer.  

                                                                                            

Storage


Storage instructions

Store at -20. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.