Product name | UVRAG Polyclonal Antibody |
Isotype | IgG |
Form | Lyophilized or Liquid |
Tested applications | WB,IHC,ELISA |
Species reactivity | Human,Mouse,Rat |
Host Species | Rabbit |
Purity | Affinity purification |
Immunogen Recombinant protein of human UVRAG Calculated molecular weight 35kDa/78kDa Observed molecular weight 100kDa Swiss Prot Q9P2Y5 Gene ID (NCBI) 7405 Alternative Names DHTX;p63;VPS38 The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user. WB 1:500 - 1:2000 IHC 1:50 - 1:100 Western blot analysis of extracts of various cell lines, using UVRAG antibody. Immunohistochemistry of paraffin-embedded human liver injury using UVRAG antibody. Immunohistochemistry of paraffin-embedded rat lung using UVRAG antibody. Immunohistochemistry of paraffin-embedded mouse lung using UVRAG antibody.
This gene complements the ultraviolet sensitivity of xeroderma pigmentosum group C cells and encodes a protein with a C2 domain. The protein activates the Beclin1-PI(3)KC3 complex, promoting autophagy and suppressing the proliferation and tumorigenicity of human colon cancer cells. Chromosomal aberrations involving this gene are associated with left-right axis malformation and mutations in this gene have been associated with colon cancer.
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
