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PAB35536 VPS37A Polyclonal Antibody

价格:    320.00元

  • Catalog:    PAB35536
  • Application:    WB,IHC,IF,ELISA
  • Reactivity:    Human,Mouse,Rat

库存 800 件

PAB35536 VPS37A Polyclonal Antibody

320.00元

Catalog : PAB35536
Application : WB,IHC,IF,ELISA
Reactivity : Human,Mouse,Rat
Product Information


Product name

VPS37A Polyclonal Antibody

Isotype

IgG

Form

Lyophilized or Liquid

Tested applications

WB,IHC,IF,ELISA

Species reactivity

Human,Mouse,Rat

Host Species

Rabbit

Purity

Affinity purification


Immunogen Information


Immunogen

Recombinant protein of human VPS37A

Calculated molecular weight

20kDa/41kDa/44kDa

Observed molecular weight 

44kDa

Swiss Prot

Q8NEZ2

Gene ID (NCBI)

137492

Alternative Names

HCRP1;PQBP2;SPG53


Application Notes


  

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

WB

1:500 - 1:2000

WB 1:500 - 1:2000

IHC

1:50 - 1:200

IHC 1:50 - 1:200

IF

1:50 - 1:200


 

    1                       

Western blot analysis of extracts of various cell lines, using VPS37A antibody.

 

 2               3                

Immunohistochemistry of paraffin-embedded rat brain using VPS37A antibody.


Immunohistochemistry of paraffin-embedded mouse stomach using VPS37A antibody.

   

Background


This gene belongs to the VPS37 family, and encodes a component of the ESCRT-I (endosomal sorting complex required for transport I) protein complex, required for the sorting of ubiquitinated transmembrane proteins into internal vesicles of multivesicular bodies. Expression of this gene is downregulated in hepatocellular carcinoma, and mutations in this gene are associated with autosomal recessive spastic paraplegia-53. A related pseudogene has been identified on chromosome 5. Alternatively spliced transcript variants have been found for this gene.                                                                                                       

Storage


Storage instructions

Store at -20. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.