欢迎来到Bioswamp武汉贝茵莱生物科技有限公司   注册   登录

PAB36097 PSPC1 Polyclonal Antibody

价格:    320.00元

  • Catalog:    PAB36097
  • Application:    WB,ELISA,IHC
  • Reactivity:    Human,Mouse

库存 800 件

PAB36097 PSPC1 Polyclonal Antibody

320.00元

Catalog : PAB36097
Application : WB,ELISA,IHC
Reactivity : Human,Mouse
Product Information

 

Product name

PSPC1 Polyclonal Antibody

Isotype

IgG

Form

Lyophilized or Liquid

Tested applications

WB,ELISA,IHC

Species reactivity

Human,Mouse

Host Species

Rabbit

Purity

Affinity purification


Immunogen Information


Immunogen

Recombinant protein of human PSPC1

Calculated molecular weight

45kDa/58kDa

Observed molecular weight 

65kDa

Swiss Prot

Q8WXF1

Gene ID (NCBI)

55269

Alternative Names

PSP1


Application Notes



The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

WB

1:500 - 1:2000

IHC

1:50 - 1:500



      blob.png

Western blot analysis of extracts of various cell lines, using PSPC1 antibody.


Background

 

This gene encodes a nucleolar protein that localizes to punctate subnuclear structures that occur close to splicing speckles, known as paraspeckles. These paraspeckles are composed of RNA-protein structures that include a non-coding RNA, NEAT1/Men epsilon/beta, and the Drosophila Behavior Human Splicing family of proteins, which include the product of this gene and the P54NRB/NONO and PSF/SFPQ proteins. Paraspeckles may function in the control of gene expression via an RNA nuclear retention mechanism. The protein encoded by this gene is found in paraspeckles in transcriptionally active cells, but it localizes to unique cap structures at the nucleolar periphery when RNA polymerase II transcription is inhibited, or during telophase. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene, which is also located on chromosome 13, has been identified


Storage


Storage instructions

Store at -20. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.