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PAB36092 MYL12A Polyclonal Antibody

价格:    320.00元

  • Catalog:    PAB36092
  • Application:    WB,ELISA,IHC
  • Reactivity:    Human

库存 800 件

PAB36092 MYL12A Polyclonal Antibody

320.00元

Catalog : PAB36092
Application : WB,ELISA,IHC
Reactivity : Human
Product Information

 

Product name

MYL12A Polyclonal Antibody

Isotype

IgG

Form

Lyophilized or Liquid

Tested applications

WB,ELISA,IHC

Species reactivity

Human

Host Species

Rabbit

Purity

Affinity purification


Immunogen Information


Immunogen

Recombinant protein of human MYL12A

Calculated molecular weight

19kDa

Observed molecular weight 

18kDa

Swiss Prot

P19105

Gene ID (NCBI)

10627

Alternative Names

HEL-S-24;MLC-2B;MLCB;MRCL3;MRLC3;MYL2B


Application Notes



The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

WB

1:500 - 1:2000

IHC

1:50 - 1:500



        blob.png

Western blot analysis of extracts of various cell lines, using MYL12A antibody.


Background


This gene encodes a nonsarcomeric myosin regulatory light chain. This protein is activated by phosphorylation and regulates smooth muscle and non-muscle cell contraction. This protein may also be involved in DNA damage repair by sequestering the transcriptional regulator apoptosis-antagonizing transcription factor (AATF)/Che-1 which functions as a repressor of p53-driven apoptosis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 8. 

 

Storage


Storage instructions

Store at -20. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.