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PAB35906 PHF1 Polyclonal Antibody

价格:    320.00元

  • Catalog:    PAB35906
  • Application:    WB,IHC,ELISA
  • Reactivity:    Human,Mouse,Rat

库存 800 件

PAB35906 PHF1 Polyclonal Antibody

320.00元

Catalog : PAB35906
Application : WB,IHC,ELISA
Reactivity : Human,Mouse,Rat
Product Information


Product name

PHF1 Polyclonal Antibody

Isotype

IgG

Form

Lyophilized or Liquid

Tested applications

WB,IHC,ELISA

Species reactivity

Human,Mouse,Rat

Host Species

Rabbit

Purity

Affinity purification


Immunogen Information


Immunogen

Recombinant protein of human PHF1

Calculated molecular weight

49kDa/62kDa

Observed molecular weight 

62kDa

Swiss Prot

O43189

Gene ID (NCBI)

5252

Alternative Names

hPHF1;MTF2L2;PCL1;PHF2;TDRD19C


Application Notes


     

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

WB

1:500 - 1:2000

IHC

1:50 - 1:200

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Western blot analysis of extracts of various cell lines, using PHF1 antibody.


Immunohistochemistry of paraffin-embedded rat brain using PHF1 antibody.

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Immunohistochemistry of paraffin-embedded human liver injury using PHF1 antibody.

Immunohistochemistry of paraffin-embedded mouse brain using PHF1 antibody.

Immunohistochemistry of paraffin-embedded mouse heart using PHF1 antibody.


Background

   

This gene encodes a Polycomb group protein. The protein is a component of a histone H3 lysine-27 (H3K27)-specific methyltransferase complex, and functions in transcriptional repression of homeotic genes. The protein is also recruited to double-strand breaks, and reduced protein levels results in X-ray sensitivity and increased homologous recombination. Multiple transcript variants encoding different isoforms have been found for this gene. 

                                                                                             

Storage


Storage instructions

Store at -20. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.