Product name | PHF1 Polyclonal Antibody |
Isotype | IgG |
Form | Lyophilized or Liquid |
Tested applications | WB,IHC,ELISA |
Species reactivity | Human,Mouse,Rat |
Host Species | Rabbit |
Purity | Affinity purification |
Immunogen Recombinant protein of human PHF1 Calculated molecular weight 49kDa/62kDa Observed molecular weight 62kDa Swiss Prot O43189 Gene ID (NCBI) 5252 Alternative Names hPHF1;MTF2L2;PCL1;PHF2;TDRD19C The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user. WB 1:500 - 1:2000 IHC 1:50 - 1:200 Western blot analysis of extracts of various cell lines, using PHF1 antibody. Immunohistochemistry of paraffin-embedded rat brain using PHF1 antibody. Immunohistochemistry of paraffin-embedded human liver injury using PHF1 antibody. Immunohistochemistry of paraffin-embedded mouse brain using PHF1 antibody. Immunohistochemistry of paraffin-embedded mouse heart using PHF1 antibody.
This gene encodes a Polycomb group protein. The protein is a component of a histone H3 lysine-27 (H3K27)-specific methyltransferase complex, and functions in transcriptional repression of homeotic genes. The protein is also recruited to double-strand breaks, and reduced protein levels results in X-ray sensitivity and increased homologous recombination. Multiple transcript variants encoding different isoforms have been found for this gene.
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |