Product name | PER1 Polyclonal Antibody |
Isotype | IgG |
Form | Lyophilized or Liquid |
Tested applications | WB,IHC,IF,ELISA |
Species reactivity | Human,Mouse,Rat |
Host Species | Rabbit |
Purity | Affinity purification |
Immunogen Recombinant protein of human PER1 Calculated molecular weight 91kDa/136kDa Observed molecular weight 160kDa Swiss Prot O15534 Gene ID (NCBI) 5187 Alternative Names hPER;PER;RIGUI The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user. WB 1:500 - 1:2000 IHC 1:50 - 1:100 IF 1:50 - 1:200 Western blot analysis of extracts of various cell lines, using PER1 antibody. Immunohistochemistry of paraffin-embedded human stomach using PER1 antibody. Immunohistochemistry of paraffin-embedded rat kidney using PER1 antibody. Immunohistochemistry of paraffin-embedded mouse stomach using PER1 antibody. Immunofluorescence analysis of U2OS cells using PER1 antibody.
This gene is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene may increase the risk of getting certain cancers. Alternative splicing has been observed in this gene; however, these variants have not been fully described.
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
