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PAB35900 NRGN Polyclonal Antibody

价格:    320.00元

  • Catalog:    PAB35900
  • Application:    WB,ELISA,IHC
  • Reactivity:    Human,Mouse,Rat

库存 800 件

PAB35900 NRGN Polyclonal Antibody

320.00元

Catalog : PAB35900
Application : WB,ELISA,IHC
Reactivity : Human,Mouse,Rat
Product Information


Product name

NRGN Polyclonal Antibody

Isotype

IgG

Form

Lyophilized or Liquid

Tested applications

WB,ELISA,IHC

Species reactivity

Human,Mouse,Rat

Host Species

Rabbit

Purity

Affinity purification


Immunogen Information


Immunogen

Recombinant protein of human NRGN

Calculated molecular weight

7kDa

Observed molecular weight 

14kDa

Swiss Prot

Q92686

Gene ID (NCBI)

4900

Alternative Names

hng;RC3


Application Notes


     

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

WB

1:500 - 1:2000

IHC

1:50 - 1:500

   blob.png                       

Western blot analysis of extracts of various cell lines, using NRGN antibody.


Background

   

Neurogranin (NRGN) is the human homolog of the neuron-specific rat RC3/neurogranin gene. This gene encodes a postsynaptic protein kinase substrate that binds calmodulin in the absence of calcium. The NRGN gene contains four exons and three introns. The exons 1 and 2 encode the protein and exons 3 and 4 contain untranslated sequences. It is suggested that the NRGN is a direct target for thyroid hormone in human brain, and that control of expression of this gene could underlay many of the consequences of hypothyroidism on mental states during development as well as in adult subjects.                                                                                              

Storage


Storage instructions

Store at -20. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.