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PAB35899 NEFH Polyclonal Antibody

价格:    320.00元

  • Catalog:    PAB35899
  • Application:    WB,IHC,ELISA
  • Reactivity:    Mouse,Rat

库存 800 件

PAB35899 NEFH Polyclonal Antibody

320.00元

Catalog : PAB35899
Application : WB,IHC,ELISA
Reactivity : Mouse,Rat
Product Information


Product name

NEFH Polyclonal Antibody

Isotype

IgG

Form

Lyophilized or Liquid

Tested applications

WB,IHC,ELISA

Species reactivity

Mouse,Rat

Host Species

Rabbit

Purity

Affinity purification


Immunogen Information


Immunogen

Recombinant protein of human NEFH

Calculated molecular weight

105kDa/112kDa

Observed molecular weight 

200kDa

Swiss Prot

P12036

Gene ID (NCBI)

4744

Alternative Names

CMT2CC;NFH


Application Notes


   

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

WB

1:500 - 1:2000

IHC

1:50 - 1:100

    blob.png                                      blob.png                     

Western blot analysis of extracts of mouse brain, using NEFH antibody.


Immunohistochemistry of paraffin-embedded mouse kidney using NEFH antibody.

 

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Immunohistochemistry of paraffin-embedded rat kidney using NEFH antibody.


Immunohistochemistry of paraffin-embedded rat cerebellum using NEFH antibody.


Background

   

Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the heavy neurofilament protein. This protein is commonly used as a biomarker of neuronal damage and susceptibility to amyotrophic lateral sclerosis (ALS) has been associated with mutations in this gene. 

                                                                                              

Storage


Storage instructions

Store at -20. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.