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PAB35892 HRG Polyclonal Antibody

价格:    320.00元

  • Catalog:    PAB35892
  • Application:    WB,IHC,ELISA
  • Reactivity:    Mouse,Rat

库存 800 件

PAB35892 HRG Polyclonal Antibody

320.00元

Catalog : PAB35892
Application : WB,IHC,ELISA
Reactivity : Mouse,Rat
Product Information


Product name

HRG Polyclonal Antibody

Isotype

IgG

Form

Lyophilized or Liquid

Tested applications

WB,IHC,ELISA

Species reactivity

Mouse,Rat

Host Species

Rabbit

Purity

Affinity purification


Immunogen Information


Immunogen

Recombinant protein of human HRG

Calculated molecular weight

59kDa

Observed molecular weight 

80kDa

Swiss Prot

P04196

Gene ID (NCBI)

3273

Alternative Names

HPRG;HRGP;THPH11


Application Notes


     

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

WB

1:500 - 1:2000

IHC

1:50 - 1:100

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Western blot analysis of extracts of mouse pancreas, using HRG antibody.


Immunohistochemistry of paraffin-embedded rat lung using HRG antibody.

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Immunohistochemistry of paraffin-embedded mouse lung using HRG antibody.


Immunohistochemistry of paraffin-embedded mouse stomach using HRG antibody.


Background

   

This histidine-rich glycoprotein contains two cystatin-like domains and is located in plasma and platelets. The physiological function has not been determined but it is known that the protein binds heme, dyes and divalent metal ions. The encoded protein also has a peptide that displays antimicrobial activity against C. albicans, E. coli, S. aureus, P. aeruginosa, and E. faecalis. It can inhibit rosette formation and interacts with heparin, thrombospondin and plasminogen. Two of the protein's effects, the inhibition of fibrinolysis and the reduction of inhibition of coagulation, indicate a potential prothrombotic effect. Mutations in this gene lead to thrombophilia due to abnormal histidine-rich glycoprotein levels. 

                                                                                             

Storage


Storage instructions

Store at -20. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.