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PAB35890 HLA-E Polyclonal Antibody

价格:    320.00元

  • Catalog:    PAB35890
  • Application:    WB,ELISA,IHC
  • Reactivity:    Human,Mouse,Rat

库存 800 件

PAB35890 HLA-E Polyclonal Antibody

320.00元

Catalog : PAB35890
Application : WB,ELISA,IHC
Reactivity : Human,Mouse,Rat
Product Information


Product name

HLA-E Polyclonal Antibody

Isotype

IgG

Form

Lyophilized or Liquid

Tested applications

WB,ELISA,IHC

Species reactivity

Human,Mouse,Rat

Host Species

Rabbit

Purity

Affinity purification


Immunogen Information


Immunogen

A synthetic peptide of human HLA-E

Calculated molecular weight

40kDa

Observed molecular weight 

45kDa

Swiss Prot

P13747

Gene ID (NCBI)

3133

Alternative Names

EA1.2;EA2.1;HLA-6.2;MHC;QA1;HLA-6.2;QA1


Application Notes


     

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

WB

1:500 - 1:2000

IHC

1:50 - 1:500

 

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Western blot analysis of extracts of various cell lines, using HLA-E antibody


Background

   

HLA-E belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-E binds a restricted subset of peptides derived from the leader peptides of other class I molecules. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail. 

                                                                                              

Storage


Storage instructions

Store at -20. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.