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PAB35888 HBA2 Polyclonal Antibody

价格:    320.00元

  • Catalog:    PAB35888
  • Application:    WB,IHC,ELISA
  • Reactivity:    Mouse,Rat

库存 800 件

PAB35888 HBA2 Polyclonal Antibody

320.00元

Catalog : PAB35888
Application : WB,IHC,ELISA
Reactivity : Mouse,Rat
Product Information


Product name

HBA2 Polyclonal Antibody

Isotype

IgG

Form

Lyophilized or Liquid

Tested applications

WB,IHC,ELISA

Species reactivity

Mouse,Rat

Host Species

Rabbit

Purity

Affinity purification


Immunogen Information


Immunogen

Recombinant protein of human HBA2

Calculated molecular weight

15kDa

Observed molecular weight 

13kDa

Swiss Prot

P69905

Gene ID (NCBI)

3040

Alternative Names

HBA-T2;HBH


Application Notes


     

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

WB

1:500 - 1:2000

IHC

1:50 - 1:100

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Western blot analysis of extracts of mouse liver, using HBA2 antibody.

Immunohistochemistry of paraffin-embedded mouse heart using HBA2 antibody.

Immunohistochemistry of paraffin-embedded mouse brain using HBA2 antibody.


Background

   

The human alpha globin gene cluster located on chromosome 16 spans about 30 kb and includes seven loci: 5'- zeta - pseudozeta - mu - pseudoalpha-1 - alpha-2 - alpha-1 - theta - 3'. The alpha-2 (HBA2) and alpha-1 (HBA1) coding sequences are identical. These genes differ slightly over the 5' untranslated regions and the introns, but they differ significantly over the 3' untranslated regions. Two alpha chains plus two beta chains constitute HbA, which in normal adult life comprises about 97% of the total hemoglobin; alpha chains combine with delta chains to constitute HbA-2, which with HbF (fetal hemoglobin) makes up the remaining 3% of adult hemoglobin. Alpha thalassemias result from deletions of each of the alpha genes as well as deletions of both HBA2 and HBA1; some nondeletion alpha thalassemias have also been reported. 

                                                                                        

Storage


Storage instructions

Store at -20. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.