BBS10 Polyclonal Antibody
Lyophilized or Liquid
Immunogen Recombinant protein of human BBS10 Calculated molecular weight 80kDa Observed molecular weight 81kDa Swiss Prot Q8TAM1 Gene ID (NCBI) 79738 Alternative Names C12orf58
Recombinant protein of human BBS10
Calculated molecular weight
Observed molecular weight
Gene ID (NCBI)
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1:200 - 1:3000
1:50 - 1:500
Western blot analysis of extracts of various cell lines, using BBS10 antibody.
This gene is a member of the Bardet-Biedl syndrome (BBS) gene family. Bardet-Biedl syndrome is an autosomal recessive disorder characterized by progressive retinal degeneration, obesity, polydactyly, renal malformation and mental retardation. The proteins encoded by BBS gene family members are structurally diverse and the similar phenotypes exhibited by mutations in BBS gene family members is likely due to their shared roles in cilia formation and function. Many BBS proteins localize to the basal bodies, ciliary axonemes, and pericentriolar regions of cells. BBS proteins may also be involved in intracellular trafficking via microtubule-related transport. The protein encoded by this gene is likely not a ciliary protein but rather has distant sequence homology to type II chaperonins. As a molecular chaperone, this protein may affect the folding or stability of other ciliary or basal body proteins. Inhibition of this protein's expression impairs ciliogenesis in preadipocytes. Mutations in this gene cause Bardet-Biedl syndrome type 10.
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.