欢迎来到Bioswamp武汉贝茵莱生物科技有限公司   注册   登录

PAB36045 NUP133 Polyclonal Antibody

价格:    320.00元

  • Catalog:    PAB36045
  • Application:    WB,ELISA,IHC
  • Reactivity:    Human

库存 800 件

PAB36045 NUP133 Polyclonal Antibody

320.00元

Catalog : PAB36045
Application : WB,ELISA,IHC
Reactivity : Human
Product Information

 

Product name

NUP133 Polyclonal Antibody

Isotype

IgG

Form

Lyophilized or Liquid

Tested applications

WB,ELISA,IHC

Species reactivity

Human

Host Species

Rabbit

Purity

Affinity purification

Immunogen Information


Immunogen

Recombinant protein of human NUP133

Calculated molecular weight

128kDa

Observed molecular weight 

129kDa

Swiss Prot

Q8WUM0

Gene ID (NCBI)

55746

Alternative Names

hNUP133


Application Notes



The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

WB

1:1000 - 1:2000

IHC

1:50 - 1:500



     blob.png

Western blot analysis of extracts of various cell lines, using NUP133 antibody.


Background


The nuclear envelope creates distinct nuclear and cytoplasmic compartments in eukaryotic cells. It consists of two concentric membranes perforated by nuclear pores, large protein complexes that form aqueous channels to regulate the flow of macromolecules between the nucleus and the cytoplasm. These complexes are composed of at least 100 different polypeptide subunits, many of which belong to the nucleoporin family. The nucleoporin protein encoded by this gene displays evolutionarily conserved interactions with other nucleoporins. This protein, which localizes to both sides of the nuclear pore complex at interphase, remains associated with the complex during mitosis and is targeted at early stages to the reforming nuclear envelope. This protein also localizes to kinetochores of mitotic  cells. 


Storage


Storage instructions

Store at -20. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.