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PAB36041 VPS33B Polyclonal Antibody

价格:    320.00元

  • Catalog:    PAB36041
  • Application:    WB,IF,ELISA,IHC
  • Reactivity:    Human,Mouse

库存 800 件

PAB36041 VPS33B Polyclonal Antibody

320.00元

Catalog : PAB36041
Application : WB,IF,ELISA,IHC
Reactivity : Human,Mouse
Product Information

 

Product name

VPS33B Polyclonal Antibody

Isotype

IgG

Form

Lyophilized or Liquid

Tested applications

WB,IF,ELISA,IHC

Species reactivity

Human,Mouse

Host Species

Rabbit

Purity

Affinity purification


Immunogen Information


Immunogen

Recombinant protein of human VPS33B

Calculated molecular weight

60kDa/70kDa

Observed molecular weight 

60kDa

Swiss Prot

Q9H267

Gene ID (NCBI)

26276

Alternative Names

hVPS33B, VPS33B , vacuolar protein sorting 33 homolog B (yeast)



Application Notes



The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

WB

1:1000 - 1:2000

IF

1:50 - 1:200

IHC

1:50 - 1:500



      blob.png

Western blot analysis of extracts of various cell lines, using VPS33B antibody.


Background


Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene is a member of the Sec-1 domain family, and encodes the human ortholog of rat Vps33b which is homologous to the yeast class C Vps33 protein. The mammalian class C vacuolar protein sorting proteins are predominantly associated with late endosomes/lysosomes, and like their yeast counterparts, may mediate vesicle trafficking steps in the endosome/lysosome pathway. Mutations in this gene are associated with arthrogryposis-renal dysfunction-cholestasis syndrome. Alternative splicing results in multiple transcript variants.

 

Storage


Storage instructions

Store at -20. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.