欢迎来到Bioswamp武汉贝茵莱生物科技有限公司   注册   登录

PAB36040 PBXIP1 Polyclonal Antibody

价格:    320.00元

  • Catalog:    PAB36040
  • Application:    WB,ELISA,IHC
  • Reactivity:    Human,Mouse,Rat

库存 800 件

PAB36040 PBXIP1 Polyclonal Antibody

320.00元

Catalog : PAB36040
Application : WB,ELISA,IHC
Reactivity : Human,Mouse,Rat
Product Information

 

Product name

PBXIP1 Polyclonal Antibody

Isotype

IgG

Form

Lyophilized or Liquid

Tested applications

WB,ELISA,IHC

Species reactivity

Human,Mouse,Rat

Host Species

Rabbit

Purity

Affinity purification


Immunogen Information


Immunogen

Recombinant protein of human PBXIP1

Calculated molecular weight

72kDa/77kDa/80kDa

Observed molecular weight 

110kDa

Swiss Prot

Q96AQ6

Gene ID (NCBI)

57326

Alternative Names

HPIP


Application Notes



The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

WB

1:1000 - 1:2000

IHC

1:50 - 1:500

           blob.png

Western blot analysis of extracts of various cell lines, using PBXIP1 antibody.  


Background


The protein encoded by this gene interacts with the PBX1 homeodomain protein, inhibiting its transcriptional activation potential by preventing its binding to DNA. The encoded protein, which is primarily cytosolic but can shuttle to the nucleus, also can interact with estrogen receptors alpha and beta and promote the proliferation of breast cancer, brain tumors, and lung cancer. Several transcript variants encoding different isoforms have been found for this gene. More variants exist, but their full-length natures have yet to be determined.


Storage


Storage instructions

Store at -20. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.