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PAB35981 PRDM2 Polyclonal Antibody

价格:    320.00元

  • Catalog:    PAB35981
  • Application:    WB,IHC,ELISA
  • Reactivity:    Rat

库存 800 件

PAB35981 PRDM2 Polyclonal Antibody

320.00元

Catalog : PAB35981
Application : WB,IHC,ELISA
Reactivity : Rat
Product Information

 

Product name

PRDM2 Polyclonal Antibody

Isotype

IgG

Form

Lyophilized or Liquid

Tested applications

WB,IHC,ELISA

Species reactivity

Rat

Host Species

Rabbit

Purity

Affinity purification


Immunogen Information


Immunogen

Recombinant protein of human PRDM2

Calculated molecular weight

25kDa/162kDa/166kDa/184kDa/188kDa

Observed molecular weight 

250kDa

Swiss Prot

Q13029

Gene ID (NCBI)

7799

Alternative Names

HUMHOXY1;KMT8;KMT8A;MTB-ZF;RIZ;RIZ1;RIZ2;HUMHOXY1;KMT8;MTB-ZF;RIZ;RIZ1;RIZ2


Application Notes



The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

WB

1:500 - 1:2000

IHC

1:50 - 1:200

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Western blot analysis of extracts of rat heart, using PRDM2 antibody.


Immunohistochemistry of paraffin-embedded rat lung using PRDM2 antibody.

 

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Immunohistochemistry of paraffin-embedded rat liver using PRDM2 antibody.


Immunohistochemistry of paraffin-embedded rat testis using PRDM2 antibody.

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Immunohistochemistry of paraffin-embedded rat brain using PRDM2 antibody.


Immunohistochemistry of paraffin-embedded rat kidney using PRDM2 antibody.

 

Background


This tumor suppressor gene is a member of a nuclear histone/protein methyltransferase superfamily. It encodes a zinc finger protein that can bind to retinoblastoma protein, estrogen receptor, and the TPA-responsive element (MTE) of the heme-oxygenase-1 gene. Although the functions of this protein have not been fully characterized, it may (1) play a role in transcriptional regulation during neuronal differentiation and pathogenesis of retinoblastoma, (2) act as a transcriptional activator of the heme-oxygenase-1 gene, and (3) be a specific effector of estrogen action. Multiple transcript variants encoding different isoforms have been found for this gene.

 

Storage


Storage instructions

Store at -20. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.