ATG4D Polyclonal Antibody
Lyophilized or Liquid
Recombinant protein of human ATG4D
Calculated molecular weight
Observed molecular weight
Gene ID (NCBI)
1:500 - 1:2000
WB 1:500 - 1:2000
1:50 - 1:200
IHC 1:50 - 1:200
1:50 - 1:500
Western blot analysis of extracts of various cell lines, using ATG4D antibody.
Immunofluorescence analysis of U2OS cells using ATG4D antibody.
Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene belongs to the autophagy-related protein 4 (Atg4) family of C54 endopeptidases. Members of this family encode proteins that play a role in the biogenesis of autophagosomes, which sequester the cytosol and organelles for degradation by lysosomes. Alternative splicing results in multiple transcript variants.
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.