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PAB35881 GBA Polyclonal Antibody

价格:    320.00元

  • Catalog:    PAB35881
  • Application:    WB,ELISA,IHC
  • Reactivity:    Human

库存 800 件

PAB35881 GBA Polyclonal Antibody

320.00元

Catalog : PAB35881
Application : WB,ELISA,IHC
Reactivity : Human
Product Information


Product name

GBA Polyclonal Antibody

Isotype

IgG

Form

Lyophilized or Liquid

Tested applications

WB,ELISA,IHC

Species reactivity

Human

Host Species

Rabbit

Purity

Affinity purification


Immunogen Information


Immunogen

Recombinant protein of human GBA

Calculated molecular weight

29kDa/50kDa/54kDa/57kDa/59kDa

Observed molecular weight 

60kDa

Swiss Prot

P04062

Gene ID (NCBI)

2629

Alternative Names

GBA1;GCB;GLUC


Application Notes


     

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

WB

1:500 - 1:2000

IHC

1:50 - 1:500

           blob.png                           

Western blot analysis of extracts of MCF-7 cells, using GBA antibody


Background

   

This gene encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants. 

                                                                                             

Storage


Storage instructions

Store at -20. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.