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PAB35880 GABPA Polyclonal Antibody

价格:    320.00元

  • Catalog:    PAB35880
  • Application:    WB,IHC,ELISA
  • Reactivity:    Human,Mouse

库存 800 件

PAB35880 GABPA Polyclonal Antibody

320.00元

Catalog : PAB35880
Application : WB,IHC,ELISA
Reactivity : Human,Mouse
Product Information


Product name

GABPA Polyclonal Antibody

Isotype

IgG

Form

Lyophilized or Liquid

Tested applications

WB,IHC,ELISA

Species reactivity

Human,Mouse

Host Species

Rabbit

Purity

Affinity purification


Immunogen Information


Immunogen

Recombinant protein of human GABPA

Calculated molecular weight

51kDa

Observed molecular weight 

56kDa

Swiss Prot

Q06546

Gene ID (NCBI)

2551

Alternative Names

E4TF1-60;E4TF1A;NFT2;NRF2;NRF2A;RCH04A07


Application Notes


     

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

WB

1:500 - 1:2000

IHC

1:50 - 1:200

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Western blot analysis of extracts of various cell lines, using GABPA antibody.

Immunohistochemistry of paraffin-embedded human uterine cancer using GABPA antibody.

Immunohistochemistry of paraffin-embedded human colon carcinoma using GABPA antibody.


Background

   

This gene encodes one of three GA-binding protein transcription factor subunits which functions as a DNA-binding subunit. Since this subunit shares identity with a subunit encoding the nuclear respiratory factor 2 gene, it is likely involved in activation of cytochrome oxidase expression and nuclear control of mitochondrial function. This subunit also shares identity with a subunit constituting the transcription factor E4TF1, responsible for expression of the adenovirus E4 gene. Because of its chromosomal localization and ability to form heterodimers with other polypeptides, this gene may play a role in the Down Syndrome phenotype. Two transcript variants encoding the same protein have been found for this gene. 

                                                                                              

Storage


Storage instructions

Store at -20. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.