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PAB35874 CRHR1 Polyclonal Antibody

价格:    320.00元

  • Catalog:    PAB35874
  • Application:    WB,IHC,ELISA
  • Reactivity:    Human,Mouse,Rat

库存 800 件

PAB35874 CRHR1 Polyclonal Antibody

320.00元

Catalog : PAB35874
Application : WB,IHC,ELISA
Reactivity : Human,Mouse,Rat
Product Information


Product name

CRHR1 Polyclonal Antibody

Isotype

IgG

Form

Lyophilized or Liquid

Tested applications

WB,IHC,ELISA

Species reactivity

Human,Mouse,Rat

Host Species

Rabbit

Purity

Affinity purification


Immunogen Information


Immunogen

Recombinant protein of human CRHR1

Calculated molecular weight

28kDa/43kDa/46kDa/47kDa/50kDa

Observed molecular weight 

60kDa

Swiss Prot

P34998

Gene ID (NCBI)

1394

Alternative Names

CRF-R;CRF-R-1;CRF-R1;CRF1;CRFR-1;CRFR1;CRH-R-1;CRH-R1;CRHR;CRHR1L


Application Notes


     

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

WB

1:500 - 1:2000

IHC

1:50 - 1:200

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    Western blot analysis of extracts of various cell lines, using CRHR1 antibody.

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Immunohistochemistry of paraffin-embedded rat brain using CRHR1 antibody.


Immunohistochemistry of paraffin-embedded mouse brain using CRHR1 antibody.


Background

   

This gene encodes a G-protein coupled receptor that binds neuropeptides of the corticotropin releasing hormone family that are major regulators of the hypothalamic-pituitary-adrenal pathway. The encoded protein is essential for the activation of signal transduction pathways that regulate diverse physiological processes including stress, reproduction, immune response and obesity. Alternative splicing results in multiple transcript variants. Naturally-occurring readthrough transcription between this gene and upstream GeneID:147081 results in transcripts that encode isoforms that share similarity with the products of this gene.  

                                                                                            

Storage


Storage instructions

Store at -20. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.