欢迎来到Bioswamp武汉贝茵莱生物科技有限公司   注册   登录

PAB35989 CYP46A1 Polyclonal Antibody

价格:    320.00元

  • Catalog:    PAB35989
  • Application:    WB,IHC,ELISA
  • Reactivity:    Human,Mouse,Rat

库存 800 件

PAB35989 CYP46A1 Polyclonal Antibody

320.00元

Catalog : PAB35989
Application : WB,IHC,ELISA
Reactivity : Human,Mouse,Rat
Product Information

 

Product name

CYP46A1 Polyclonal Antibody

Isotype

IgG

Form

Lyophilized or Liquid

Tested applications

WB,IHC,ELISA

Species reactivity

Human,Mouse,Rat

Host Species

Rabbit

Purity

Affinity purification


Immunogen Information


Immunogen

Recombinant protein of human CYP46A1

Calculated molecular weight

38kDa/45kDa/56kDa

Observed molecular weight 

57kDa

Swiss Prot

Q9Y6A2

Gene ID (NCBI)

10858

Alternative Names

CP46;CYP46

 

Application Notes



The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

WB

1:500 - 1:2000

IHC

1:50 - 1:100

image.png          image.png                          

Western blot analysis of extracts of various cell lines, using CYP46A1 antibody.


Immunohistochemistry of paraffin-embedded human prostate using CYP46A1 antibody.

 


Background


This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein is expressed in the brain, where it converts cholesterol to 24S-hydroxycholesterol. While cholesterol cannot pass the blood-brain barrier, 24S-hydroxycholesterol can be secreted in the brain into the circulation to be returned to the liver for catabolism.

 

Storage


Storage instructions

Store at -20. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.