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PAB35865 ALAD Polyclonal Antibody

价格:    320.00元

  • Catalog:    PAB35865
  • Application:    WB,IHC,ELISA
  • Reactivity:    Human

库存 800 件

PAB35865 ALAD Polyclonal Antibody

320.00元

Catalog : PAB35865
Application : WB,IHC,ELISA
Reactivity : Human
Product Information


Product name

ALAD Polyclonal Antibody

Isotype

IgG

Form

Lyophilized or Liquid

Tested applications

WB,IHC,ELISA

Species reactivity

Human

Host Species

Rabbit

Purity

Affinity purification


Immunogen Information


Immunogen

Recombinant protein of human ALAD

Calculated molecular weight

36kDa/39kDa

Observed molecular weight 

36kDa

Swiss Prot

P13716

Gene ID (NCBI)

210

Alternative Names

ALADH;PBGS


Application Notes


     

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

WB

1:500 - 1:2000

IHC

1:50 - 1:100

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Western blot analysis of extracts of various cell lines, using ALAD antibody.


Immunohistochemistry of paraffin-embedded human stomach using ALAD antibody.


Background

   

The ALAD enzyme is composed of 8 identical subunits and catalyzes the condensation of 2 molecules of delta-aminolevulinate to form porphobilinogen (a precursor of heme, cytochromes and other hemoproteins). ALAD catalyzes the second step in the porphyrin and heme biosynthetic pathway; zinc is essential for enzymatic activity. ALAD enzymatic activity is inhibited by lead and a defect in the ALAD structural gene can cause increased sensitivity to lead poisoning and acute hepatic porphyria. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms.   

                                                                                              

Storage


Storage instructions

Store at -20. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.