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PAB35857 NCOR2 Polyclonal Antibody

价格:    320.00元

  • Catalog:    PAB35857
  • Application:    WB,ELISA,IHC
  • Reactivity:    Human

库存 800 件

PAB35857 NCOR2 Polyclonal Antibody

320.00元

Catalog : PAB35857
Application : WB,ELISA,IHC
Reactivity : Human
Product Information


Product name

NCOR2 Polyclonal Antibody

Isotype

IgG

Form

Lyophilized or Liquid

Tested applications

WB,ELISA,IHC

Species reactivity

Human

Host Species

Rabbit

Purity

Affinity purification


Immunogen Information


Immunogen

Recombinant protein of human NCOR2

Calculated molecular weight

81kDa/268kDa/273kDa/274kDa

Observed molecular weight 

180kDa

Swiss Prot

Q9Y618

Gene ID (NCBI)

9612

Alternative Names

CTG26;N-CoR2;SMAP270;SMRT;SMRTE;SMRTE-tau;TNRC14;TRAC;TRAC-1;TRAC1


Application Notes


     

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

WB

1:500 - 1:2000

IHC

1:50 - 1:500

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Western blot analysis of extracts of various cell lines, using NCOR2 antibody.


Background

   

This gene encodes a nuclear receptor co-repressor that mediates transcriptional silencing of certain target genes. The encoded protein is a member of a family of thyroid hormone- and retinoic acid receptor-associated co-repressors. This protein acts as part of a multisubunit complex which includes histone deacetylases to modify chromatin structure that prevents basal transcriptional activity of target genes. Aberrant expression of this gene is associated with certain cancers. Alternate splicing results in multiple transcript variants encoding different isoforms.  

                                                                                              

Storage


Storage instructions

Store at -20. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.