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PAB35998 MIB1 Polyclonal Antibody

价格:    320.00元

  • Catalog:    PAB35998
  • Application:    WB,ELISA,IHC
  • Reactivity:    Human,Mouse,Rat

库存 800 件

PAB35998 MIB1 Polyclonal Antibody

320.00元

Catalog : PAB35998
Application : WB,ELISA,IHC
Reactivity : Human,Mouse,Rat
Product Information

 

Product name

MIB1 Polyclonal Antibody

Isotype

IgG

Form

Lyophilized or Liquid

Tested applications

WB,ELISA,IHC

Species reactivity

Human,Mouse,Rat

Host Species

Rabbit

Purity

Affinity purification


Immunogen Information


Immunogen

Recombinant protein of human MIB1

Calculated molecular weight

110kDa

Observed molecular weight 

110kDa

Swiss Prot

Q86YT6

Gene ID (NCBI)

57534

Alternative Names

DIP-1;DIP1;LVNC7;MIB;ZZANK2;ZZZ6


Application Notes



The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

WB

1:500 - 1:2000

IHC

1:50 - 1:500

           image.png

Western blot analysis of extracts of various cell lines, using MIB1 antibody.

 

Background


This gene encodes a protein containing multiple ankyrin repeats and RING finger domains that functions as an E3 ubiquitin ligase. The encoded protein positively regulates Notch signaling by ubiquitinating the Notch receptors, thereby facilitating their endocytosis. This protein may also promote the ubiquitination and degradation of death-associated protein kinase 1 (DAPK1). 

 

Storage


Storage instructions

Store at -20. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.