PLK3 Polyclonal Antibody
Lyophilized or Liquid
Immunogen Recombinant protein of human PLK3 Calculated molecular weight 71kDa Observed molecular weight 72kDa Swiss Prot Q9H4B4 Gene ID (NCBI) 1263 Alternative Names CNK;FNK;PLK-3;PRK
Recombinant protein of human PLK3
Calculated molecular weight
Observed molecular weight
Gene ID (NCBI)
1:500 - 1:2000
1:50 - 1:500
Western blot analysis of extracts of various cell lines, using PLK3 antibody.
The protein encoded by this gene is a member of the highly conserved polo-like kinase family of serine/threonine kinases. Members of this family are characterized by an amino-terminal kinase domain and a carboxy-terminal bipartite polo box domain that functions as a substrate-binding motif and a cellular localization signal. Polo-like kinases are important regulators of cell cycle progression. This gene has also been implicated in stress responses and double-strand break repair. In human cell lines, this protein is reported to associate with centrosomes in a microtubule-dependent manner, and during mitosis, the protein becomes localized to the mitotic apparatus. Expression of a kinase-defective mutant results in abnormal cell morphology caused by changes in microtubule dynamics and mitotic arrest followed by apoptosis.
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.