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PAB36024 MTHFD1 Polyclonal Antibody

价格:    320.00元

  • Catalog:    PAB36024
  • Application:    WB,ELISA,IHC
  • Reactivity:    Human,Mouse,Rat

库存 800 件

PAB36024 MTHFD1 Polyclonal Antibody

320.00元

Catalog : PAB36024
Application : WB,ELISA,IHC
Reactivity : Human,Mouse,Rat
Product Information

 

Product name

MTHFD1 Polyclonal Antibody

Isotype

IgG

Form

Lyophilized or Liquid

Tested applications

WB,ELISA,IHC

Species reactivity

Human,Mouse,Rat

Host Species

Rabbit

Purity

Affinity purification

 

Immunogen Information


Immunogen

Recombinant protein of human MTHFD1

Calculated molecular weight

101kDa

Observed molecular weight 

115kDa

Swiss Prot

P11586

Gene ID (NCBI)

4522

Alternative Names

MTHFC;MTHFD


Application Notes



The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

WB

1:200 - 1:2000

IHC

1:50 - 1:500



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Western blot analysis of extracts of various cell lines, using MTHFD1 antibody.

 

Background


This gene encodes a protein that possesses three distinct enzymatic activities, 5,10-methylenetetrahydrofolate dehydrogenase, 5,10-methenyltetrahydrofolate cyclohydrolase and 10-formyltetrahydrofolate synthetase. Each of these activities catalyzes one of three sequential reactions in the interconversion of 1-carbon derivatives of tetrahydrofolate, which are substrates for methionine, thymidylate, and de novo purine syntheses. The trifunctional enzymatic activities are conferred by two major domains, an aminoterminal portion containing the dehydrogenase and cyclohydrolase activities and a larger synthetase domain.  


Storage


Storage instructions

Store at -20. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.