MTHFD1 Polyclonal Antibody
Lyophilized or Liquid
Immunogen Recombinant protein of human MTHFD1 Calculated molecular weight 101kDa Observed molecular weight 115kDa Swiss Prot P11586 Gene ID (NCBI) 4522 Alternative Names MTHFC;MTHFD
Recombinant protein of human MTHFD1
Calculated molecular weight
Observed molecular weight
Gene ID (NCBI)
1:200 - 1:2000
1:50 - 1:500
Western blot analysis of extracts of various cell lines, using MTHFD1 antibody.
This gene encodes a protein that possesses three distinct enzymatic activities, 5,10-methylenetetrahydrofolate dehydrogenase, 5,10-methenyltetrahydrofolate cyclohydrolase and 10-formyltetrahydrofolate synthetase. Each of these activities catalyzes one of three sequential reactions in the interconversion of 1-carbon derivatives of tetrahydrofolate, which are substrates for methionine, thymidylate, and de novo purine syntheses. The trifunctional enzymatic activities are conferred by two major domains, an aminoterminal portion containing the dehydrogenase and cyclohydrolase activities and a larger synthetase domain.
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.