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PAB35855 CD163 Polyclonal Antibody

价格:    320.00元

  • Catalog:    PAB35855
  • Application:    WB,ELISA,IHC
  • Reactivity:    Human,Mouse,Rat

库存 800 件

PAB35855 CD163 Polyclonal Antibody

320.00元

Catalog : PAB35855
Application : WB,ELISA,IHC
Reactivity : Human,Mouse,Rat
Product Information


Product name

CD163 Polyclonal Antibody

Isotype

IgG

Form

Lyophilized or Liquid

Tested applications

WB,ELISA,IHC

Species reactivity

Human,Mouse,Rat

Host Species

Rabbit

Purity

Affinity purification


Immunogen Information


Immunogen

Recombinant protein of human CD163

Calculated molecular weight

121kDa/124kDa/125kDa

Observed molecular weight 

180kDa

Swiss Prot

Q86VB7

Gene ID (NCBI)

9332

Alternative Names

M130;MM130;SCARI1


Application Notes


     

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

WB

1:500 - 1:1000

IHC

1:50 - 1:500

              blob.png                    

Western blot analysis of extracts of various cell lines, using CD163 Antibody.


Background

   

The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.  

                                                                                            

Storage


Storage instructions

Store at -20. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.