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PAB36018 ALDH7A1 Polyclonal Antibody

价格:    320.00元

  • Catalog:    PAB36018
  • Application:    WB,IHC,IF,ELISA
  • Reactivity:    Human,Mouse,Rat

库存 800 件

PAB36018 ALDH7A1 Polyclonal Antibody

320.00元

Catalog : PAB36018
Application : WB,IHC,IF,ELISA
Reactivity : Human,Mouse,Rat
Product Information

 

Product name

ALDH7A1 Polyclonal Antibody

Isotype

IgG

Form

Lyophilized or Liquid

Tested applications

WB,IHC,IF,ELISA

Species reactivity

Human,Mouse,Rat

Host Species

Rabbit

Purity

Affinity purification


Immunogen Information


Immunogen

Recombinant protein of human ALDH7A1

Calculated molecular weight

51kDa/55kDa/58kDa

Observed molecular weight 

58kDa

Swiss Prot

P49419

Gene ID (NCBI)

501

Alternative Names

ATQ1;EPD;PDE


Application Notes



The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

WB

1:1000 - 1:4000

IHC

1:50 - 1:200

IF

1:50 - 1:200



  blob.png

Western blot analysis of extracts of various cell lines, using ALDH7A1 antibody.


Background


The protein encoded by this gene is a member of subfamily 7 in the aldehyde dehydrogenase gene family. These enzymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. This particular member has homology to a previously described protein from the green garden pea, the 26g pea turgor protein. It is also involved in lysine catabolism that is known to occur in the mitochondrial matrix. Recent reports show that this protein is found both in the cytosol and the mitochondria, and the two forms likely arise from the use of alternative translation initiation sites. An additional variant encoding a different isoform has also been found for this gene. Mutations in this gene are associated with pyridoxine-dependent epilepsy. Several related pseudogenes have also been identified. 

 

Storage


Storage instructions

Store at -20. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.