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PAB36017 DDX50 Polyclonal Antibody

价格:    320.00元

  • Catalog:    PAB36017
  • Application:    WB,IHC,ELISA
  • Reactivity:    Human,Mouse

库存 800 件

PAB36017 DDX50 Polyclonal Antibody

320.00元

Catalog : PAB36017
Application : WB,IHC,ELISA
Reactivity : Human,Mouse
Product Information

 

Product name

DDX50 Polyclonal Antibody

Isotype

IgG

Form

Lyophilized or Liquid

Tested applications

WB,IHC,ELISA

Species reactivity

Human,Mouse

Host Species

Rabbit

Purity

Affinity purification


Immunogen Information


Immunogen

Recombinant protein of human DDX50

Calculated molecular weight

82kDa

Observed molecular weight 

105kDa

Swiss Prot

Q9BQ39

Gene ID (NCBI)

79009

Alternative Names

GU2;GUB;mcdrh;RH-II/GuB


Application Notes



The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

WB

1:200 - 1:2000

IHC

1:50 - 1:200

 

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Western blot analysis of extracts of various cell lines, using DDX50 antibody.


Background


DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box enzyme that may be involved in ribosomal RNA synthesis or processing. This gene and DDX21, also called RH-II/GuA, have similar genomic structures and are in tandem orientation on chromosome 10, suggesting that the two genes arose by gene duplication in evolution. This gene has pseudogenes on chromosomes 2, 3 and 4. Alternative splicing of this gene generates multiple transcript variants, but the full length nature of all the other variants but one has not been defined.  


Storage


Storage instructions

Store at -20. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.