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PAB35842 FBXO22 Polyclonal Antibody

价格:    320.00元

  • Catalog:    PAB35842
  • Application:    WB,ELISA,IHC
  • Reactivity:    Human

库存 800 件

PAB35842 FBXO22 Polyclonal Antibody

320.00元

Catalog : PAB35842
Application : WB,ELISA,IHC
Reactivity : Human
Product Information


Product name

FBXO22 Polyclonal Antibody

Isotype

IgG

Form

Lyophilized or Liquid

Tested applications

WB,ELISA,IHC

Species reactivity

Human

Host Species

Rabbit

Purity

Affinity purification


Immunogen Information


Immunogen

Recombinant protein of human FBXO22

Calculated molecular weight

4kDa/30kDa/44kDa

Observed molecular weight 

45kDa

Swiss Prot

Q8NEZ5

Gene ID (NCBI)

26263

Alternative Names

FBX22;FISTC1


Application Notes


The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

WB

1:500 - 1:2000

IHC

1:50 - 1:500

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Western blot analysis of extracts of various cell lines, using FBXO22 antibody.

     

Background

   

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and, as a transcriptional target of the tumor protein p53, is thought to be involved in degradation of specific proteins in response to p53 induction. Alternative splicing results in multiple transcript variants.

                                                                                           

Storage


Storage instructions

Store at -20. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.