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PAB36232 RGS10 Polyclonal Antibody

价格:    320.00元

  • Catalog:    PAB36232
  • Application:    WB,ELISA,IHC
  • Reactivity:    Human,Rat

库存 800 件

PAB36232 RGS10 Polyclonal Antibody

320.00元

Catalog : PAB36232
Application : WB,ELISA,IHC
Reactivity : Human,Rat
Product Information

 

Product name

RGS10 Polyclonal Antibody

Isotype

IgG

Form

Lyophilized or Liquid

Tested applications

WB,ELISA,IHC

Species reactivity

Human,Rat

Host Species

Rabbit

Purity

Affinity purification


Immunogen Information


Immunogen

Recombinant protein of human RGS10

Calculated molecular weight

19kDa/20kDa/21kDa

Observed molecular weight 

20kDa

Swiss Prot

O43665

Gene ID (NCBI)

6001

Alternative Names

regulator of G-protein signaling 10


Application Notes



The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

WB

1:200 - 1:500

IHC

1:50 - 1:500

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Western blot analysis of extracts of various cell lines, using RGS10 antibody.


Background


Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 10 belongs to this family. All RGS proteins share a conserved 120-amino acid sequence termed the RGS domain. This protein associates specifically with the activated forms of the two related G-protein subunits, G-alphai3 and G-alphaz but fails to interact with the structurally and functionally distinct G-alpha subunits. Regulator of G protein signaling 10 protein is localized in the nucleus. Two transcript variants encoding different isoforms have been found for this gene.   


Storage


Storage instructions

Store at -20. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.