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PAB36231 PSMB3 Polyclonal Antibody

价格:    320.00元

  • Catalog:    PAB36231
  • Application:    WB,ELISA,IHC
  • Reactivity:    Human,Mouse,Rat

库存 800 件

PAB36231 PSMB3 Polyclonal Antibody

320.00元

Catalog : PAB36231
Application : WB,ELISA,IHC
Reactivity : Human,Mouse,Rat
Product Information

 

Product name

PSMB3 Polyclonal Antibody

Isotype

IgG

Form

Lyophilized or Liquid

Tested applications

WB,ELISA,IHC

Species reactivity

Human,Mouse,Rat

Host Species

Rabbit

Purity

Affinity purification


Immunogen Information


Immunogen

Recombinant protein of human PSMB3

Calculated molecular weight

22kDa

Observed molecular weight 

23kDa

Swiss Prot

P49720

Gene ID (NCBI)

5691

Alternative Names

HC10-II


Application Notes



The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

WB

1:500 - 1:2000

IHC

1:50 - 1:500

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Western blot analysis of extracts of various cell lines, using PSMB3 antibody.

 

Background


The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. The 26 S proteasome may be involved in trinucleotide repeat expansion, a phenomenon which is associated with many hereditary neurological diseases. Pseudogenes have been identified on chromosomes 2 and 12. Alternative splicing results in multiple transcript variants  


Storage


Storage instructions

Store at -20. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.