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PAB35834 DDX39B Polyclonal Antibody

价格:    320.00元

  • Catalog:    PAB35834
  • Application:    WB,IHC,ELISA
  • Reactivity:    Human,Mouse,Rat

库存 800 件

PAB35834 DDX39B Polyclonal Antibody

320.00元

Catalog : PAB35834
Application : WB,IHC,ELISA
Reactivity : Human,Mouse,Rat
Product Information


Product name

DDX39B Polyclonal Antibody

Isotype

IgG

Form

Lyophilized or Liquid

Tested applications

WB,IHC,ELISA

Species reactivity

Human,Mouse,Rat

Host Species

Rabbit

Purity

Affinity purification


Immunogen Information


Immunogen

Recombinant protein of human DDX39B

Calculated molecular weight

48kDa/50kDa

Observed molecular weight 

49kDa

Swiss Prot

Q13838

Gene ID (NCBI)

7919

Alternative Names

BAT1;D6S81E;UAP56


Application Notes


     

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

WB

1:500 - 1:2000

IHC

1:100 - 1:200

 

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Western blot analysis of extracts of various cell lines, using DDX39B antibody.

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Immunohistochemistry of paraffin-embedded human prostate cancer using DDX39B antibody.

Immunohistochemistry of paraffin-embedded human esophagus using DDX39B antibody.

Immunohistochemistry of paraffin-embedded mouse brain using DDX39B antibody.


Background


This gene encodes a member of the DEAD box family of RNA-dependent ATPases that mediate ATP hydrolysis during pre-mRNA splicing. The encoded protein is an essential splicing factor required for association of U2 small nuclear ribonucleoprotein with pre-mRNA, and it also plays an important role in mRNA export from the nucleus to the cytoplasm. This gene belongs to a cluster of genes localized in the vicinity of the genes encoding tumor necrosis factor alpha and tumor necrosis factor beta. These genes are all within the human major histocompatibility complex class III region. Mutations in this gene may be associated with rheumatoid arthritis. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on both chromosomes 6 and 11. Read-through transcription also occurs between this gene and the upstream ATP6V1G2 (ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2) gene.  

                                                                                            

Storage


Storage instructions

Store at -20. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.