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PAB36229 SERPINB6 Polyclonal Antibody

价格:    320.00元

  • Catalog:    PAB36229
  • Application:    WB,ELISA,IHC
  • Reactivity:    Human

库存 800 件

PAB36229 SERPINB6 Polyclonal Antibody

320.00元

Catalog : PAB36229
Application : WB,ELISA,IHC
Reactivity : Human
Product Information

 

Product name

SERPINB6 Polyclonal Antibody

Isotype

IgG

Form

Lyophilized or Liquid

Tested applications

WB,ELISA,IHC

Species reactivity

Human

Host Species

Rabbit

Purity

Affinity purification


Immunogen Information


Immunogen

Recombinant protein of human SERPINB6

Calculated molecular weight

42kDa

Observed molecular weight 

43kDa

Swiss Prot

P35237

Gene ID (NCBI)

5269

Alternative Names

CAP;DFNB91;MSTP057;PI-6;PI6;PTI;SPI3


Application Notes



The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

WB

1:500 - 1:2000

IHC

1:50 - 1:500

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Western blot analysis of extracts of various cell lines, using SERPINB6 antibody.


Background


The protein encoded by this gene is a member of the serpin (serine proteinase inhibitor) superfamily, and ovalbumin(ov)-serpin subfamily. It was originally discovered as a placental thrombin inhibitor. The mouse homolog was found to be expressed in the hair cells of the inner ear. Mutations in this gene are associated with nonsyndromic progressive hearing loss, suggesting that this serpin plays an important role in the inner ear in the protection against leakage of lysosomal content during stress, and that loss of this protection results in cell death and sensorineural hearing loss. Alternatively spliced transcript variants have been found for this gene.   


Storage


Storage instructions

Store at -20. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.