欢迎来到Bioswamp武汉贝茵莱生物科技有限公司   注册   登录

PAB35833 XPC Polyclonal Antibody

价格:    320.00元

  • Catalog:    PAB35833
  • Application:    WB,IHC,ELISA
  • Reactivity:    Human

库存 800 件

PAB35833 XPC Polyclonal Antibody

320.00元

Catalog : PAB35833
Application : WB,IHC,ELISA
Reactivity : Human
Product Information


Product name

XPC Polyclonal Antibody

Isotype

IgG

Form

Lyophilized or Liquid

Tested applications

WB,IHC,ELISA

Species reactivity

Human

Host Species

Rabbit

Purity

Affinity purification


Immunogen Information


Immunogen

Recombinant protein of human XPC

Calculated molecular weight

15kDa/101kDa/105kDa

Observed molecular weight 

130kDa

Swiss Prot

Q01831

Gene ID (NCBI)

7508

Alternative Names

p125;RAD4;XP3;XPCC


Application Notes


  

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

WB

1:500 - 1:2000

IHC

1:50 - 1:100

blob.png  blob.png                         

Western blot analysis of extracts of various cell lines, using XPC antibody.


Immunohistochemistry of paraffin-embedded human liver cancer using XPC antibody.

   

Background

   

This gene encodes a component of the nucleotide excision repair (NER) pathway. There are multiple components involved in the NER pathway, including Xeroderma pigmentosum (XP) A-G and V, Cockayne syndrome (CS) A and B, and trichothiodystrophy (TTD) group A, etc. This component, XPC, plays an important role in the early steps of global genome NER, especially in damage recognition, open complex formation, and repair protein complex formation. Mutations in this gene or some other NER components result in Xeroderma pigmentosum, a rare autosomal recessive disorder characterized by increased sensitivity to sunlight with the development of carcinomas at an early age. Alternatively spliced transcript variants have been found for this gene.  

                                                                                              

Storage


Storage instructions

Store at -20. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.