APP Polyclonal Antibody
Lyophilized or Liquid
A synthetic peptide of human APP
Calculated molecular weight
Observed molecular weight
Gene ID (NCBI)
APP; AAA; ABETA; ABPP; AD1; APPI; CTFgamma; CVAP; PN-II; PN2; preA4; amyloid beta A4 protein
1:500 - 1:2000
1:50 - 1:200
1:50 - 1:200
Western blot analysis of extracts of various cell lines, using APP antibody.
Immunohistochemistry of paraffin-embedded
rat brain using APP antibody.
Immunohistochemistry of paraffin-embedded human colon using APP antibody
Immunohistochemistry of paraffin-embedded human colon carcinoma using APP antibody
paraffin-embedded mouse cerebellum
using APP antibody.
Immunofluorescence analysis of HeLa cells using APP antibody
This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. In addition, two of the peptides are antimicrobial peptides, having been shown to have bacteriocidal and antifungal activities. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene.
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.